Gene finding with Hidden Markov Models

Materials for class on Monday, July 20, 2020

Contents

Slides

• View lectures slide in your browser (html)

• Aki’s S4 objects for Markov Models

Action Items

• Oct 29 Midterm

Points of Reflection

• Our model is very simple. Name some of aspects of DNA-protein interactions that are not captured by our model.

• What other aspects of gene regulation are not well modelled by our approach?

• How could we improve our mdoel to better reflect the bioogical reality of transcription factors, binding sites and gene regulation in general?